Learn more about the premium ingredients of Entropy:
- Resveratrol -- The anti-aging component of red wine. More...
Resveratrol is a substance found in the skin of red grapes and is believed to be responsible for the beneficial effects of red wine. Scientific evidence suggests that resveratrol has cardioprotective properties and is linked with slowing down the aging process. Entropy contains the equivalent of 10 glasses of red wine, without the alcohol.
 Resveratrol improves health and survival of mice on a high-calorie diet
, Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, Sinclair DA, Nature
2006 444 (7117): 337-42.
 Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
, Pearson KJ, et al. Cell Metabolism
2008 8 (2): 157-68.
 Therapeutic potential of resveratrol: the in vivo evidence.
Baur JA, Sinclair DA Nature Reviews Drug Discovery
2006 5 (6): 493-506.
 Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate
Valenzano DR, Terzibasi E, Genade T, Cattaneo A, Domenici L, Cellerino A (2006). Current Biology
2005 16 (3): 296-300.
- Green Tea -- A powerful antioxidant that has been shown to aid in weight loss. Standardized to 40 mg EGCG. More...
Green tea contains catechin polyphenols which help promote fat loss and control obesity besides being a powerful antioxidant. The studies below show that green tea is helpful in achieving weight loss beyond
and despite its small caffeine content. "The green tea extract may play a role in the control of body composition via sympathetic activation of thermogenesis, fat oxidation, or both." "Tea catechins are thus shown here for the first time to have the anti-obesity effects in humans." "The current results showed that supplementation of green tea extract is beneficial for antiobesity by the suppression of lipogenesis."
 Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans.
Dulloo AG, Duret C, Rohrer D, Girardier L, Mensi N, Fathi M, Chantre P, Vandermander J. The American journal of clinical nutrition
1999, vol. 70, num. 6, pp. 1040-1045.
 Green tea and thermogenesis: interactions between catechin-polyphenols, caffeine and sympathetic activity.
A G Dulloo, J Seydoux, L Girardier, P Chantre and J Vandermander International Journal of Obesity
. February 2000, Volume 24, Number 2, Pages 252-258.
 Anti-obesity Effects of Tea Catechins in Humans.
Hase T. Komine Y., Meguro S., Takeda Y., Takahashi H., Matsui Y., Tokimitsu I., Shimaski H., Itakura H. Journal of Japan Oil Chemists' Society
vol.50, no.7, pp 599-605(2001).
 Tea catechins suppress accumulation of body fat in humans.
Nagao T., Meguro S., Soga S., Otsuka A., Tomonobu K., Fumoto S., Chikama A., Mori K., Yuzawa M., Watanabe H., Hase T., Tanaka Y., Tokimitsu I., Shimasaki H. and Itakura H. Journal of Oleo Science
, vol. 50 (2001) , no. 9, pp. 717.
 Antilipogenic effect of green tea extract in C57BL/6J-Lep ob/ob mice.
Kim HJ, Jeon SM, Lee MK, Jung UJ, Shin SK, Choi MS. Phytotherapy research
, 2009 Apr;23(4):467-71.
- Açaí Berry -- Potent anti-oxidant. May help reduce the effects of aging on mental cognition (learning and memory). More...
Açaí (pronounced ah-sah-eeh) is the berry from the açaí palm tree found in areas of the Amazon. Açaí is very popular in Brazil due to its strong anti-oxidant effect. It has been shown to "positively impact learning and memory in the aged animal, reducing the impact of stress-related cellular signals and increasing the capacity of neurons to maintain proper functioning during aging." Açaí is a natural, feel-good fruit that is important in any healthy diet, especially for those fighting effects of aging.
 Recent advances in berry supplementation and age-related cognitive decline.
Willis, Lauren M; Shukitt-Hale, Barbara; Joseph, James A. Current Opinion in Clinical Nutrition and Metabolic Care
, January 2009 - Volume 12 - Issue 1 - p 91-94
 Berry Fruits: Compositional Elements, Biochemical Activities, and the Impact of Their Intake on Human Health, Performance, and Disease.
Navindra P. Seeram, Journal of Agricultural and Food Chemistry
, 2008, 56 (3), pp 627-629.
 Pharmacokinetics of Anthocyanins and Antioxidant Effects after the Consumption of Anthocyanin-Rich Aai Juice and Pulp (Euterpe oleraceaMart.) in Human Healthy Volunteers.
Susanne U. Mertens-Talcott, Jolian Rios, Petra Jilma-Stohlawetz, Lisbeth A. Pacheco-Palencia, Bernd Meibohm, Stephen T. Talcott and Hartmut Derendorf, Journal of Agricultural and Food Chemistry
, 2008, 56 (17), pp 7796-7802
- L-Carnitine -- An amino acid essential to fat metabolism that has been shown to help sustain endurance, reduce fatigue and improve muscle recovery in athletes. More...
L-Carnitine is an amino-acid produced by the body in small quantities. L-carnitine is used by the body's metabolism to expend energy (burn fatty acids into usable energy via the citric acid cycle). L-carnitine has been shown to reduce fatigue from repetitive exercise, to reduce oxidative damage and delay muscular fatigue as well as helped VO2max (a measure of physical fitness) in athletes. Supplementation is recommended as the body ages, since the body's own production decreases with time.
 Effects of l-carnitine loading on the aerobic and anaerobic performance of endurance athletes.
C. Marconi, G. Sassi, A. Carpinelli and P. Cerretelli, European Journal of Applied Physiology and Occupational Physiology
, vol. 54(2), August, 1985, pp 131-135.
 L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress.
Jeff S. Volek, William J. Kraemer, Martyn R. Rubin, Ana L. Gómez, Nicholas A. Ratamess, and Paula Gaynor, American Journal of Physiology, Endocrinology and Metabolism
, vol. 282(2), pp. 474-482, February 2002.
 L-carnitine supplementation attenuates intermittent hypoxia-induced oxidative stress and delays muscle fatigue in rats.
Arkadeb Dutta, Koushik Ray, Vijay K. Singh, Praveen Vats, Som N. Singh and Shashi B. Singh, Experimental Physiology
, October 2008, 93, 1139-1146.
- Ginkgo Biloba -- A potent brain stimulant. More...
Ginkgo is a traditional Chinese herb used to improve brain function. Recent studies show that ginkgo improved performance in tests of attention and memory.
 Proof of efficacy of the ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia.
Kanowski S, Herrmann WM, Stephan K, Wierich W, Hörr R., Pharmacopsychiatry
, 1996 Mar;29(2):47-56.
 Ginkgo biloba for cerebral insufficiency.
J Kleijnen and P Knipschild, British Journal of Clinical Pharmacology
. 1992 October; 34(4): 352-358.
 Differential cognitive effects of Ginkgo biloba after acute and chronic treatment in healthy young volunteers.
Sarah Elsabagh1, David E. Hartley, Osama Ali, Elizabeth M. Williamson and Sandra E. File. Psychopharmacology
. Volume 179, Number 2, May 2005, pp 437-446.
- Panax Ginseng -- Potent anti-oxidant, has many benefits including anti-inflammatory properties. Taken with ginkgo biloba, may enhance memory and cognition in middle-aged people. More...
Ginseng, especially the Panax kind when taken with ginkgo biloba, may enhance memory and cognition in middle-aged people. Ginseng is the root of an asian herb, used for centuries as a brain stimulant. Today, we know it is a potent anti-oxidant, and has many benefits including anti-inflammatory properties. Panax ginseng was found to improve a number of different aspects of memory, including working and long-term memory.
 Panax ginseng.
Kiefer,D.; Pantuso,T., American Family Physician
. 2003 Oct 15; 68(8): 1539-42.
 The memory enhancing effects of a Ginkgo biloba/Panax ginseng combination in healthy middle-aged volunteers.
Wesnes, K. A.; Ward, T.; McGinty, A.; Petrini, O. Psychopharmacology
. Vol 152(4), Nov 2000, 353-361.
 Antidiabetic Effects of Panax ginseng Berry Extract and the Identification of an Effective Component.
Anoja S. Attele, Yun-Ping Zhou, Jing-Tian Xie, Ji An Wu, Liu Zhang, Lucy Dey, William Pugh, Paul A. Rue, Kenneth S. Polonsky and Chun-Su Yuan, Diabetes
. June 2002 vol. 51 no. 6 1851-1858
- B Complex -- Vitamins from the B complex are vital for delivering energy to the cells and for a healthy life. Niacin (B3) supports a strong heart, B12 helps reduce fatigue. More...
Vitamins for the B complex are necessary for healthy living. They are specially important for cell energy. Vegetarians are at increased risk of deficiency of vitamins B, given that the most abundant source is from meats. Supplementation of B12
is specially important as we age, since the body has trouble absorbing it. "Students who took extra thiamine [B1
] more than doubled their scores on the clear-headedness and mood test". Perhaps more troubling is that all but one of these students had a normal level of thiamine when the study started. Niacin (B3
) has been used in higher doses to treat cardiac problems[4,5]. B12
and folic acid were shown to fight homocysteine levels which is linked with heart disease[7,8].
 Vegetarian diets : nutritional considerations for athletes.
Venderley A.M., Campbell W.W., Sports Med.
 Thiamine's Mood-Mending Qualities.
Richard N. Podell, Nutrition Science News
. January 1999.
 Riboflavin (vitamin B-2) and health.
Hilary J Powers, American Journal of Clinical Nutrition
, Vol. 77, No. 6, 1352-1360, June 2003.
 Niacin and cholesterol: role in cardiovascular disease (review).
Ganji S.H., Kamanna V.S., Kashyap M.L. Journal of nutritional biochemistry
. 2003 Jun;14(6):298-305.
 Niacin decreases removal of high-density lipoprotein apolipoprotein A-I but not cholesterol ester by Hep G2 cells. Implication for reverse cholesterol transport.
Jin F.Y., Kamanna V.S., Kashyap M.L. Arteriosclerosis, thrombosis, and vascular biology.
 Dietary Supplement Fact Sheet: Vitamin B12
Office of Dietary Supplements, National Institutes of Health.
 Effects of folic acid and combinations of folic acid and vitamin B-12 on plasma homocysteine concentrations in healthy, young women.
Brönstrup A, Hages M, Prinz-Langenohl R, Pietrzik K. American journal of clinical nutrition.
 Multivitamin/mineral supplementation improves plasma B-vitamin status and homocysteine concentration in healthy older adults consuming a folate-fortified diet.
McKay DL, Perrone G, Rasmussen H, Dallal G, Blumberg JB. Journal of nutrition
- Guarana -- Energy booster, rich in caffeine. Guarana improves memory performance and increases alertness and mood. More...
Guarana helps improve memory performance and increase alert and content mood ratings, and this effect was found to not be solely attributed to caffeine. Guarana is also rich in caffeine. Entropy's caffeine content is 60mg, which is about as much as a cup of regular coffee.
 A double-blind, placebo-controlled, multi-dose evaluation of the acute behavioural effects of guaraná in humans.
Haskell CF, Kennedy DO, Wesnes KA, Milne AL, Scholey AB. Journal of psychopharmacology.
 Pharmacological activity of Guarana (Paullinia cupana Mart.) in laboratory animals.
Espinola EB, Dias RF, Mattei R, Carlini EA. Journal of Ethnopharmacology
, 1997 Feb;55(3):223-9.